Topic: ASP.Net controls that are not compatible with AJAX UpdatePanel Control
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The following ASP.NET controls are not compatible with partial-page updates, and are therefore not supported inside an UpdatePanel control:
o        TreeView and Menu controls.
o        Web Parts controls. For more information, see ASP.NET Web Parts Controls.
o        FileUpload controls when they are used to upload files as part of an asynchronous postback.
o       GridView and DetailsView controls when their EnableSortingAndPagingCallbacks property is set to true. The default is false.
o       Login, PasswordRecovery, ChangePassword, and CreateUserWizard controls whose contents have not been converted to editable templates.
o    The Substitution control.